3-Chloro-4-methylboronic acid

3-Chloro-4-methylboronic acid - Names and Identifiers

Name	3-Chloro-4-methylphenylboronic acid
Synonyms	AKOS BRN-0174 3-Chloro-p-tolylboronic acid 3-Chloro-4-methylboronic acid 3-Chloro-4-Methylphenylboronic 3-Chloro-4-methylphenylboronic acid 3-CHLORO-4-METHYLPHENYLBORONIC ACID 3-CHLORO-4-METHYLBENZENEBORONIC ACID
CAS	175883-63-3
InChI	InChI=1/C7H8BClO2/c1-5-2-3-6(8(10)11)4-7(5)9/h2-4,10-11H,1H3
InChIKey	YTJUYWRCAZWVSX-UHFFFAOYSA-N

3-Chloro-4-methylboronic acid - Physico-chemical Properties

Molecular Formula	C7H8BClO2
Molar Mass	170.4
Density	1.26±0.1 g/cm3(Predicted)
Melting Point	210-216°C
Boling Point	317.3±52.0 °C(Predicted)
Flash Point	145.7°C
Vapor Presure	0.000163mmHg at 25°C
Appearance	White crystal
Color	White
pKa	7.82±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.549
MDL	MFCD04039010

3-Chloro-4-methylboronic acid - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29163990
Hazard Class	IRRITANT

3-Chloro-4-methylboronic acid - Introduction

acid is an organic compound with the chemical formula C7H8BClO2. The following is a description of its nature, use, preparation and safety information:

Nature:
acid is a colorless or light yellow crystalline solid, soluble in alcohol, ether and chlorinated solvents, slightly soluble in water. It has a melting point of about 171-173°C and a boiling point of 370-380°C. The compounds generally have high melting points and relatively strong stability.

Use:
Cr acid is an important reagent in organic synthesis and is widely used in different reaction processes of organic synthesis. It can be used as reagents for acylation, electrophilic fluorination, hydroxides, dehydrogenase inhibitors, and ligands for palladium-catalyzed coupling reactions.

Method:
The preparation methods of Calcium acid are more diverse, and the most common method is obtained by the reaction of 4-methylphenylboronic acid and cuprous chloride. Common synthetic methods also include the reaction of borane with 3-chlorobromobenzene, the reaction of borane with 3-fluorobromobenzene, etc.

Safety Information:
acid is generally a stable and relatively safe compound under normal use conditions. However, during Operation, appropriate protective measures should be taken to avoid contact with skin and eyes, and to avoid inhaling its dust or vapor. In the event of inadvertent contact, flush the affected area immediately with plenty of water and seek medical help immediately. In addition, it should be stored in a sealed container, away from fire and high temperature environment. In the use or storage process, please strictly abide by the relevant safety procedures.

Last Update：2024-04-10 22:29:15